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Infertility Overview
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Infertility: Infertility in Men

In men, infertility can be caused by low or abnormal sperm production or function, blockages that prevent the delivery of sperm, illnesses, injuries, chronic health problems, and lifestyle choices.

 

Male infertility, accounting for up to 30% of total infertility cases (50% when combined with female infertility), is often linked to a low sperm count. In half the time, the cause remains unknown.

In the past 45 years, median sperm counts have dropped by 50% (from 101 mill/ml in 1973 to 49 mill/ml in 2018), and the percentage of decline per year doubled, increasing from 1.16% post-1972 to 2.64% post-2000 (1). Although it is estimated that worldwide 1 in 10 men are infertile (2), there's no approved treatment yet for male infertility.

Our company is dedicated to researching solutions, providing hope to couples dealing with fertility challenges.​​

References:

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(1) Levine et al. Temporal trends in sperm count: a systematic review and meta-regression analysis of samples collected globally in the 20th and 21st centuries. Hum Reprod Update. 2023 Mar 1;29(2):157-176.

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(2) Rimmer et al. A core outcome set for future male infertility research: development of an international consensus. Fertil Steril. 2025 Apr 11:S0015-0282(25)00157-8.

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